Supplements and Safety

The Arivale Perspective on the Recent Frontline and PBS Reports

Reaffirming Arivale’s application of robust, scientifically validated evidence to govern interventions

In response to the Supplements and Safety report produced by Frontline and PBS, Arivale reaffirms its application of robust, scientifically validated evidence as criteria that governs all recommended interventions.

Personalized Recommendations

360_degrees_of_you_iconAlongside a high bar for evidence-based interventions, Arivale coaches strive to personalize all recommendations to our Pioneers’ unique biochemical, genetic and behavioral makeup.

Whenever possible, Arivale matches validated dietary and lifestyle recommendations with a Pioneer’s highly individualized situation. There are times when, using these criteria, Arivale coaches will recommend a nutritional supplement as an adjunct to the dietary and lifestyle intervention.

With these tenets as a foundation, we believe the Supplements and Safety report overlooks several key considerations in the matter of fish oil supplements.

First, all nutritional supplements (type, dose and duration) must be custom-tailored to each person. In this manner, we closely match supplement recommendations with well-established documentation of their efficacy in specific conditions. We expressly do not make blanket recommendations that everyone should take nutritional supplements.

The 2014 JAMA article cited in the Supplements and Safety report mentions several randomized clinical trials (RCTs) that did not show benefit of fish oil supplementation. It is unclear whether the fish oil was prescribed from the basis of a deficient Essential Fatty Acid laboratory result, measured markers of inflammation or high triglycerides. When paired with these objective laboratory findings, fish oil has a well-documented track record of efficacy. In fact, the Endocrine Society recommends the use of moderate to higher dose fish oil, either alone or with statins, as a treatment for hypertriglyceridemia.(1)

Finally, the Jan 19 New York Times Well blog concludes by stating:“Proponents of fish oil supplements argue that omega-3 fatty acids are essential for heart function and promote overall health. Experts say there is no doubt about that. But there is no clinical evidence that taking high doses in supplement form is beneficial for most people.”

We agree with this summation and remind that while high-dose fish oil is likely not beneficial for most people, targeted doses matched to scientifically validated findings can play a role in optimizing wellness.

Ensuring High Quality and Safety

Arivale also strongly agrees with the need to employ rigorous quality control and safety standards within the supplement industry and applauds the efforts of Frontline and PBS to shine light on this topic. Arivale coaches and clinicians scrutinize all recommended supplements to ensure that the various considered brands maintain the highest quality standards. In the case of fish oil, Arivale coaches recommend a brand that adheres to and exceeds the stringent European Pharmacopoeia Standard (EPS) as well as the voluntary standards set by the Council for Responsible Nutrition (CRN). These standards reduce toxins like peroxides, heavy metals, dioxins, and PCBs to levels lower than the industry requirements.


Source: Lars Berglund, John D. Brunzell, Anne C. Goldberg, Ira J. Goldberg, Frank Sacks, Mohammad Hassan Murad and AFHS. Guidelines Evaluation and Treatment of Hypertriglyceridemia : J Clin Endocrinol Metab. 2012;(97):2969–89.

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